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I actually dose these a little heavy at 2.2 to 2.3 mg for good measure. I've done it this way for years =) Fantastic alternative to Xanax (alprazolam). Per PsychonautWiki: 'Anecdotal reports suggest that in terms of its relative potency, 1 mg of etizolam is approximately equivalent to 0.5 mg of alprazolam (Xanax), 0.5 mg of clonazepam (Klonopin), or 10 mg of diazepam (Valium).