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It is known for its stimulating and euphoric effects, often compared to those of MDMA (Ecstasy) and cocaine. Mephedrone was commonly sold online as a legal high in the late 2000s, but it has since been banned in many countries due to its potential for abuse and harmful effects. Key Details About Mephedrone: Effects: Mephedrone produces stimulating effects such as euphoria, increased energy, enhanced sociability, and heightened alertness.