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For that reason, DMT was known as the "businessman's trip" during the 1960s in the United States, as a user could access the full depth of a psychedelic experience in considerably less time than with other substances such as LSD or magic mushrooms.6 DMT can be inhaled, injected, vaped or orally ingested, and its effects depend on the dose. When inhaled or injected, the effects last a short period of time: about 5 to 15 minutes.