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Less common side effects include loss of appetite, nervousness, abdominal pain, diarrhea, urine retention, dyspnea, and hiccups. In high doses, or in some persons not tolerant to opioids, oxycodone can cause shallow breathing, slowed heart rate, cold/clammy skin, pauses in breathing, low blood pressure, constricted pupils, circulatory collapse, respiratory arrest, and death.