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However, there are other common effects, including: dry mouth warm flushing of the skin heavy feeling in the arms and legs nausea and vomiting severe itching clouded mental functioning going “on the nod,” a back-and-forth state of being conscious and semiconscious Long-Term Effects of heroin People who use heroin over the long term may develop: insomnia collapsed veins for people who inject the drug damaged tissue inside the nose for people who sniff or snort it infection of the heart lining and valves...