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Because they increase wakefulness, various amphetamines have been used by the military, by pilots, truck drivers, and other workers to keep functioning past their normal limits Amphetamine was discovered in 1887 and exists as two enantiomers: levoamphetamine and dextroamphetamine. Amphetamine properly refers to the racemic free base, or equal parts of the enantiomers levoamphetamine and dextroamphetamine in their pure amine forms.